Back in the 70s many folks thought they knew what the future of computing looked like: everyone sharing time-slices of a few huge computers. After all, they saw that CPU cycles, the main computing cost, were cheaper on bigger machines. This analysis, however, ignored large administrative overheads in dealing with shared machines. People eagerly grabbed personal computers (PCs) to avoid those overheads, even though PC CPU cycles were more expensive.
Similarly, people seem to make lots of assumptions when they refer to "full-scale nanotechnology." This phrase seems to elicit images of fridge sized home appliances that, when plugged in and stocked with a few "toner cartridges", makes anything a CAD system can describe, and so quickly and cheaply that only the most price-sensitive folks would consider making stuff any other way. It seems people learned too much from the PC case, thinking everything must become personal and local. (Note computing is now getting less local.) But there is no general law of increasingly local production.
The locality of manufacturing, and computing as well, have always come from tradeoffs between economies and dis-economies of scale. Things can often be made cheaper in big centralized plants, especially if located near key inputs. When processing bulk materials, for example, there is a rough 2/3 cost power law: throughput goes as volume, while the cost to make and manage machinery tends to go as surface area. But it costs more to transport products from a few big plants. Local plants can offer more varied products, explore more varied methods, and deliver cheaper and faster.
Innovation and adaption to changing conditions can be faster or slower at centralized plants, depending on other details. Politics sometimes pushes for local production to avoid dependence on foreigners, and at other times pushes for central production to make succession more difficult. Smaller plants can better avoid regulation, while larger ones can gain more government subsidies. When formal intellectual property is weak (the usual case), producers can prefer to make and sell parts instead of selling recipes for making parts.
Often producers don’t even really know how they achieve the quality they do. Manufacturers today make great use of expensive intelligent labor; while they might prefer to automate all production, they just don’t know how. It is not at all obvious how feasible is "full nanotech," if defined as fully automated manufacturing, in the absence of full A.I. Nor is it obvious that even fully automated manufacturing would be very local production. The optimal locality will depend on how all these factors change over the coming decades; don’t be fooled by confident conclusiosn based on only one or two of these factors. More here.
@Vassar
"fairly easy (e.g. a large but routine engineering project) with 10^22 FLOPS"
Just to ground this discussion a bit, I'm sure everyone knows that currently only IBM's Roadrunner has been clocked for the full petaflop (10^15), altho' its Blue Gene should "soon" be upgraded/upgradeable to run at 3 petaflops. (I might also watch Yoyotech, your friendly neighborhood supercomputer geeks, for this in the relatively near future, say less than 5 years.)
The full yottaflop (10^24) despite what seems like impossible situation - larger than an office building! would take more power than the entire NYC FiDi! or whatever - may however be practically conceivable, if those folks at Evolved Machines are really onto something.
Large Scale manufacturers will always have an advantage with commodity products. What's not clear about the future is what Large Scale means. Currently it means centralized manufacturing but in the future we may see more advanced distributed manufacturing.
Yes, we already distribute our manufacturing, parts are made in one location and shipped off to another for assembly, then drop shipped or warehoused then shipped off to local merchants. With nanotech capabilities and sufficient AI or even without it, we should be able to make this process even more distributed.
Rather than shipping parts to assembly houses we would be shipping raw nano-materials (the new 'parts') to local 'distribution' houses which would only need enough space for a few large production units. Due to the physical nature of their products these local distributors would still specialize in particular product lines - scaffolds for nano-materials still take up space. They may even do so because they are official distributors for a particular brand of products and would carry out the 'manufacturing', distribution and marketing of the products to the local populace - tailoring the specifications to that market as only a regional producer can.
I can see a future where intellectual property does play a large role in this... big brands create blueprints (patented/copyrighted of course) for various products and then license out the rights to modify/customize that blueprint for said regional markets. Big brands may even provide the startup capital for their franchises in the same way they do now for their storefronts.
A typical shopping experience would be like going to a high end furniture store or auto dealership. You shop the floor models and pick out your base model, then select features (color/texture/material, optional sizes, style, etc) and place your order. For a large item it would be delivered to your home.. smaller items would be made while you wait. Obviously there would still be pre-fab'd units available for those in a hurry or whom don't care for customization - these would be cheaper and would be what the production units churn out when not producing a custom product. Overruns might go off to someplace like Costco where you can buy in bulk and where there is warehouse space available.
SO buying all kinds of products would be a much more personal experience and variations on products which currently can't be made due to the need for consistent moulds and dies would be possible.